CHOLEDOCHOLITHIASIS stones in common bile duct Signs and symptoms 50% asymptomatic tenderness in RUQ or epigastriu...
CHOLEDOCHOLITHIASIS
- stones in common bile duct
Signs and symptoms
- 50% asymptomatic
- tenderness in RUQ or epigastrium biliary pain with intermittent chills, fever or fluctuating jaundice
- episodic cholangitis
- spectrum from healthy to icterus, toxicity, high fever and chills
Diagnostic investigations
- increased bilirubin (<10), ALP
- leukocytosis often > 20 x 109/L
- U/S - duct dilatation, does not detect CBD stones
- ERCP (if no previous cholecystectomy) otherwise PTC appropriate
Treatment
- antibiotics, NG tube, IV hydration
- if no improvement in 2-4 days then ERCP/PTC+sphincterotomy or surgery with CBD exploration and laparoscopic cholecystectomy
DIAGNOSTIC EVALUATION OF BILIARY TREE
U/S is diagnostic procedure of choice
Oral cholecystography
- Opaque drug taken night before, look for filling defect (stones)
- failure of gallbladder to opacify indicative of complete obstruction by stone or unable to concentrate because of inflammation
HIDA scan
- radioisotope technetium excreted in high concentrations in bile
- highly suggestive of acute cholecystitis when gallbladder not visualized due to cystic duct obstruction 4 hours after injection reliable when bilirubin > 20
PTC
- injection of contrast via needle passed through hepatic parenchyma
- useful for proximal bile duct lesions or when ERCP fails
- antibiotic premedication always, contraindicated with cholangitis
ERCP -(Endoscopic Retrograde Cholangiopancreatography)
- opacification of bile and pancreatic ducts possible
- preferred method to demonstrate CBD stones and periampullary region