1. What interstitial lung disease does this dude have? A. NSIP B. DIP C. UIP D. COP 2. What is the trademark feature of this lung process? A...
1. What interstitial lung disease does this dude have?
A. NSIP
B. DIP
C. UIP
D. COP
2. What is the trademark feature of this lung process?
A. Ground Glass
B. Nodules (Centrilobular)
C. Nodules (Perilymphatic)
D. Honeycombing
3 What is the “buzzword” for this disease?
A. Honey combing
B. Reticulation
C. Sub pleural sparing
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Correct answers
1. What interstitial lung disease does this dude have?
NSIP
2. What is the trademark feature of this lung process?
Ground Glass
3. What is the “buzzword” for this disease?
Sub pleural sparing
NSIP
Less Common than UIP. Even though the name infers that its non-specific, it’s actually a specific entity.
Key features :
• Histologically it is homogeneous inflammation or fibrosis (UIP was heterogeneous).
• It is a common pattern in collagen vascular disease, and drug reactions.
• It is the most common interstitial lung disease seen with scleroderma
• There are two flavors: cellular (the good one – with mostly ground glass), and fibrotic (the bad one with bronchiectasis)
• CT Findings:
• Distribution is lower lobe, posterior, and peripheral predominant
• Sparing of the immediate sub pleural lung from the ground glass is seen in 50% of cases, and is “classic”
• Honeycombing (when present, and lower lobe predominant) is “the most useful HRCT feature” to differentiate histologic UIP from either fibrotic or cellular NSIP. In other words, lower lobe honeycombing = UIP
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