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Esthesioneuroblastoma

    1.  What is the diagnosis?  A.  SNUC B.   Inverting Papilloma C.   Fungal Sinusitis D.  Esthesioneuroblastoma 2. This cancer originates ...

    1.  What is the diagnosis? 

A.  SNUC

B.   Inverting Papilloma

C.   Fungal Sinusitis

D.  Esthesioneuroblastoma

2. This cancer originates from?

A.   The submucosal cells of the sinonasal tract

B.  The middle turbinate

C.   The olfactory cells

D.  The osseous maxilla

3. What is the classic finding (s) for the tumor?

A.   Enhancement, and T2 bright

B.  Bony destruction, and T2 bright

C.  Peritumoral cysts, and “Dumbbell” appearance

D.  Large Mass without MIBG uptake

4. The typical age for this tumor is?

A.   <20

B.  Bimodal: 20s and 50s

C.  Always > 60

D.   It’s random, can occur at any age.

Answers :

1.  What is the diagnosis?

A.  SNUC

B.   Inverting Papilloma

C.   Fungal Sinusitis

D.  Esthesioneuroblastoma

2. This cancer originates from?

A.   The submucosal cells of the sinonasal tract

B.  The middle turbinate

C.  The olfactory cells

D.  The osseous maxilla

3. What is the classic finding (s) for the tumor?

A.   Enhancement, and T2 bright

B.  Bony destruction, and T2 bright

C.  Peritumoral cysts, and “Dumbbell” appearance

D.  Large Mass without MIBG uptake

4. The typical age for this tumor is?

A.   <20

B.  Bimodal: 20s and 50s

C.  Always > 60

D.   It’s random, can occur at any age.

ESTHESIONEUROBLASTOMA

Essentially a neuroblastoma of the olfactory cells.

Key feature

– Has a bimodal distribution-occurs 20s and 50s

– Starts growing at the cribriform plate then (usually) grows down and up, wasting in the middle. This creates a dumbbell appearance.

– The characteristic finding is peritumoral cysts at the top. If they want a single diagnosis they have to show you this (otherwise it’s a squamous cell -which is more common).

– They enhance avidly (duh, they are tumors).

– They take up MIBG, because they are basically a neuroblastoma.