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ALLERGIC BRONCHOPULMONARY ASPERGILLOSIS (ABPA)

“ Usually occurs in the context of chronic asthma or cystic fibrosis.  Aspergillus  organisms are inhaled by an atopic host and cause a hype...

Usually occurs in the context of chronic asthma or cystic fibrosis. Aspergillus organisms are inhaled by an atopic host and cause a hypersensitivity reaction. It is the most common pulmonary cause of an eosinophilia. Treatment is with steroids.
Plain film
•  Migratory patchy foci of consolidation.

•  ‘Tram track’ appearance (i.e. gross bronchiectasis), central/upper zones is classic.

•  Tubular opacities are classic—these are dilated airways plugged with mucous, known as the ‘finger in glove’ appearance.
•  Atelectasis from airway obstruction.
HRCT 
•  Hyperdense mucoid impaction of central and upper lobe airways giving rise to bronchiectasis.
•  Bronchiectasis is varicose or saccular.
•  Centrilobular nodules and masses are features, not pleural effusions.
•  Chronic disease leads to upper zone fibrosis.
•  Air-trapping—gives a mosaic pattern of attenuation
Allergic bronchopulmonary aspergillosis. Chest x-ray demonstrating gross central bronchiectasis with tubular opacities. These represent mucous-filled bronchi known as the ‘finger in glove’ appearance.
 Allergic bronchopulmonary aspergillosis. CT image demonstrating gross central varicose bronchiectasis (white arrow) with mucous-filled bronchi.