Computed tomography • Normal liver is 55-60 HU post-contrast, usually 8-10 HU more than the spleen. • Most liver tumours are arterialise...
Computed tomography
• Normal liver is 55-60 HU post-contrast, usually 8-10 HU more than the spleen.
• Most liver tumours are arterialised and so show maximal enhancement in the arterial phase (20-40 seconds postcontrast).
Magnetic resonance imaging
• Normal liver returns a signal similar to muscle, except on inversion recovery.
• On T1, spleen is darker than liver; on T2, spleen is brighter than liver.
• Gadolinium is the most commonly used contrast agent.
• Superparamagnetic iron oxide particles shorten T1 and T2 and are taken up by the reticuloendothelial system.
• Hepatocyte-specific agents (e.g. mangafodipir) accumulate in hepatocytes and are then excreted via the bile—normal liver parenchymal enhancement & biliary system.
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