“ Presents in infancy. Histology shows increased density of Rosenthal fibres. MRI • Progressive demyelination beginning with the frontal l...
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Presents in infancy. Histology shows increased density of Rosenthal fibres.
MRI
• Progressive demyelination beginning with the frontal lobes and eventually involving the entire hemispheres
• Enhancement following contrast administration is seen in Alexander’s disease
• Brain enlargement,macrocephaly
• Brain enlargement,macrocephaly
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