“ Due to an excess of growth hormone (GH) in a mature skeleton (‘gigantism’ results from GH excess in an immature skeleton). Most commonly d...
“
Due to an excess of growth hormone (GH) in a mature skeleton (‘gigantism’ results from GH excess in an immature skeleton). Most commonly due to a benign pituitary adenoma. Associated with an increased heel pad thickness >25 mm
SPINE X-RAY
• Posterior vertebral scalloping
• Increased anterior-posterior (AP) and transverse diameters of the vertebral bodies
• Narrowed interpedicular distance
• Spur formation
• Calcified discs
HAND X-RAY
• Spade appearance of terminal tufts of phalanges
MRI
• Enlarged, enhancing pituitary gland (note microadenomas enhance less than surrounding gland)
• Macroadenoma if >10 mm
”
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