“ Rare disease that is m ost common in smokers aged 30-40 years, thought to be due to antigen exposure (hence it predominates in the upper z...
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Rare disease that is most common in smokers aged 30-40 years, thought to be due to antigen exposure
(hence it predominates in the upper zones of the lungs).
HRCT
• Early on, nodules are most common in the mid-upper zones.
• As the disease progresses, the nodules undergo cystic degeneration.
• Eventually, the cysts may coalesce to form a honeycomb pattern.
• The presence of 3-10-mm nodules and cysts in the upper zones in a smoker is strongly suggestive of histiocytosis.
Langerhans cell histiocytosis. HRCT image demonstrating bilateral lung cysts with coalescence into a honeycomb pattern (white arrow).
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