“ Non-malignant proliferation of fibrous tissue affecting the mediastinum. Wide range of causes including infectious (histoplasmosis and TB)...
“
Non-malignant proliferation of fibrous tissue affecting the mediastinum. Wide range of causes including infectious (histoplasmosis and TB), inflammatory (retroperitoneal fibrosis and orbital pseudotumour) and iatrogenic (radiotherapy and drug reaction). Tends to affect the young. Described as focal (80%—usually secondary to TB or histoplasmosis) or diffuse (20%—mostly inflammatory). It is the most common benign cause of SVC obstruction.
FOCAL
CT
• 2-5-cm calcified (80% calcified) mass compressing pulmonary vasculature leading to right heart strain
• Peribronchial cuffing, septal thickening and wedge-shaped areas of pulmonary infarction
DIFFUSE FORM
CT
• Soft tissue encasement of mediastinal structures with infiltration of fat planes
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