“ Mesothelioma accounts for about 1% of thoracic neoplasms, but it is the most common pleural malignanc y. Mostly it is nodular (70%), with ...
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Mesothelioma accounts for about 1% of thoracic neoplasms, but it is the most common pleural malignancy. Mostly it is nodular (70%), with the rest being diffuse, and it originates in the parietal pleura. There is a strong association with previous asbestos exposure, with a latency period of up to 40 years.
More than 50% of cases of mesothelioma invade the pericardium
70-80% have pleural effusions
Crocidolite asbestos fibres are of greater carcinogenic potential than chrysotile fibres
Metastases to the ipsilateral lung are seen in 50-60%
PLAIN FILM
• Unilateral pleural effusion, pleural thickening and volume loss
• Calcified pleural plaques
CT
• Nodular pleural thickening with encasement and mediastinal involvement.
• Check for extension below the diaphragm, which denotes T4 disease (rare).
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