SPIO and gadolinium are useful for the detection of hepatocellular carcinoma in cirrhotic patients in whom the detection is difficult with g...
SPIO and gadolinium are useful for the detection of hepatocellular carcinoma in cirrhotic patients in whom the detection is difficult with gadolinium alone.
• SPIO is taken up by hepatocytes and causes marked T2 shortening (i.e. signal loss).
• The lesion composed of abnormal cells does not take up SPIO and therefore appears high signal.
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