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"ADENOMA"

This is a benign tumour composed of proliferating hepatocytes . It typically affects young women on the oral contraceptive pill or may be li...

This is a benign tumour composed of proliferating hepatocytes. It typically affects young women on the oral contraceptive pill or may be linked to glycogen storage disease. There may be rapid growth during pregnancy. There is a small risk of malignant transformation (1%).
US

•  Typically 8-10 cm in size, hyperechoic lesion (may mimic haemangioma).
•  80% solitary, right lobe.
•  Central areas of low echogenicity caused by haemorrhage or necrosis.
•  Check for subcapsular/intraperitoneal haematoma.

CT

•  Hypodense.
•  Transient arterial enhancement, isodense by portal venous phase.
•  There may be mixed enhancement with hypodense patches due to necrosis and degeneration (as they outgrow vascular supply).
•  Check for subcapsular or intraperitoneal haematoma.

MRI

•  High T1 (most other lesions are low T1) due to glycogen, fat and haemorrhage
•  Isointense on in-phase T1, loses signal on out-of-phase images
•  Isointense on T2
•  Immediate and intense enhancement with rapid washout

NUCLEAR MEDICINE

•  Reduced tracer uptake on technetium-99m-labelled sulphur colloid scan (due to non-functioning Kupffer cells)

ANGIOGRAPHY

•  Large peripheral arteries feeding into the tumour mass