“ Complications post-cardiac transplantation include infection and post-transplant lymphoproliferative disorder (PTLD). INFECTION. This is ...
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Complications post-cardiac transplantation include infection and post-transplant lymphoproliferative disorder (PTLD).
This is the most common complication following cardiac transplant. Infections in the first month posttransplant are more likely bacterial. After that, opportunistic viral and fungal infections are more common.
Plain film
• Single or multiple pulmonary nodules may represent Nocardia or Aspergillus infection.
• Aspergillus is more common 2 months post-transplant. Nocardia tends to occur later (e.g. 5 months).
PTLD
Non-specific complication mostly occurring within 1 year of transplant. Affects about 10% of solid organ recipients. It is due to B- or T-cell proliferation, usually following Epstein-Barr virus (EBV) infection. Responds rapidly to a reduction in immunosuppression or alternatively rituximab.
Plain film
• Single or multiple well-defined, slow-growing lung nodules
• Consolidation less common
• Hilar or mediastinal lymph node enlargement.
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