1. What is the diagnosis? A. Lymphoma (not treated) B. RA C. Fibrosing Mediastinitis D. Mediastinal Lipomatosis 2. What is the “classic caus...
1. What is the diagnosis?
A. Lymphoma (not treated)
B. RA
C. Fibrosing Mediastinitis
D. Mediastinal Lipomatosis
2. What is the “classic cause” (not necessarily the most common)?
A. Histoplasmosis
B. EBV
C. AIDS
D. Varicella
3. What is the dreaded complication when present in this location?
A. Metastasis to the myocardium
B. Metastasis to the lung parenchyma
C. Superior Vena Cava Syndrome
D. MI
[sociallocker id=”615″]
Correct answers :
1. What is the diagnosis?
C. Fibrosing Mediastinitis
2. What is the “classic cause” (not necessarily the most common)?
A. Histoplasmosis
3. What is the dreaded complication when present in this location?
C. Superior Vena Cava Syndrome
Fibrosing Mediastinitis
Non malignant fibrous tissue proliferative condition occurring within the mediastinum.
Key Features
• It’s classically caused by histoplasmosis (but the most common cause is actually idiopathic).
• Other causes include TB, radiation, and Sarcoid.
• It’s a soft tissue mass with calcifications that infiltrates the normal fat planes.
• It has been known to cause superior vena cava syndrome.
• It’s associated with retroperitoneal fibrosis when idiopathic – in the “IgG4” spectrum / associated disorders.
• IgG4s that go together (if you see one think of the others… the test writers will):
• Fibrosing Mediastinitis
• Retroperitoneal Fibrosis
• Autoimmune Pancreatitis
• Tubulointerstitial nephritis
• Orbital Pseudotumor
• Basically all the weird fibrosing shit
[/sociallocker]
