Page Nav

HIDE

Grid

GRID_STYLE
latest

"RENAL CELL CARCINOMA (RCC)"

“ Most common renal malignancy. Often incidental, more common in men and peaks from ages 50-70 years . In total, 70% are clear cell adenocar...

Most common renal malignancy. Often incidental, more common in men and peaks from ages 50-70 years. In total, 70% are clear cell adenocarcinomas. Consider any solid mass in the kidney as RCC until proven otherwise. RCC metastasises to lung, liver, bone, adrenals and pancreas.
US

•  Heterogeneous lobulated lesion, either hypo-reflective or mildly hyper-reflective.
•  Cystic areas are haemorrhage/necrosis.
•  Peripheral vascularity on colour Doppler.
•  Check the inferior vena cava (IVC) and renal veins with Doppler—may show low flow or thrombus in lumen.

CT
•  Look for a mass with heterogeneous enhancement (triple-phase CT).
•  May appear cystic (i.e. Bosniak 3/4).
•  A poorly enhancing solid mass could represent a papillary RCC (these are hypovascular).
•  Areas of low density are likely to represent haemorrhage or necrosis.
•  Nodules in perinephric fat suggest tumour spread (fat stranding does not).
•  Invasion of renal veins or IVC indicates T3 disease—look for an enhancing filling defect with expansion of the vessel (‘bland’ thrombus does not enhance).
•  Extension beyond Gerota fascia indicates T4 disease.
•  Metastases may be hypervascular soft tissue lesions/destructive bone lesions.