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"METASTASES"

“ Common, mostly from the lungs, breast, melanoma, gastrointestinal tract and renal.  Lymphoma (mostly non-Hodgkin) may also spread to the a...

Common, mostly from the lungs, breast, melanoma, gastrointestinal tract and renal. Lymphoma (mostly non-Hodgkin) may also spread to the adrenals.
CT

•  Small lesions that are difficult to distinguish from benign adenoma; stability over 6 months suggests benignity.
•  Expect delayed washout on adrenal CT.
•  Large masses with a heterogeneous appearance (e.g. central necrosis, haemorrhage) and irregular borders suggest frank malignancy.

NUCLEAR MEDICINE
•  PET/CT is useful for assessing indeterminate lesions—sensitive and specific for differentiating benign from malignant disease.