“ Causes are primary (parathyroid tumour), secondary (most commonly renal failure) or tertiary (autonomous hypersecretion of parathyroid hor...
“
Causes are primary (parathyroid tumour), secondary (most commonly renal failure) or tertiary (autonomous hypersecretion of parathyroid hormone [PTH] from longstanding secondary disease). The presence of increased PTH results in increased osteoclast action, bone resorption, increased plasma calcium and thence increased bone formation.
PLAIN FILM
- Osteopenia is the hallmark (may include sacroiliac joints, symphysis pubis and distal clavicles).
- Chrondrocalcinosis.
- Vertebral osteosclerosis may cause a ‘rugger jersey’ spine appearance where endplate sclerosis alternates with osteopenia—this is characteristic of secondary hyperparathyroidism due to renal failure (i.e. renal osteodystrophy).
- Bone softening: basilar invagination, vertebral collapse.
- Brown tumours are seen in primary hyperparathyroidism—these are lytic, expansile lesions that mimic metastases or myeloma, typically in the mandible, ribs or pelvis.
- Osteitis fibrosa cystica was a term historically used to describe advanced skeletal disease in primary hyperparathyroidism.
HAND X-RAY
- Subperiosteal erosion along the radial aspect of the phalanges of the middle and index fingers.
”
- For Radiology Cases, Discussion join: Radiology Made Easy on Facebook
- Subscribe to our youtube channel for FRCR radiology case discussion
- Join our Telegram group: Radiology Made Easy
