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"HYPOXIC ISCHAEMIC INJURY IN PREMATURITY"

“ More common than term Hypoxic–ischaemic brain injury—due to more risk factors and impaired cerebral autoregulation . Severe Hypoxic–ischae...

More common than term Hypoxic–ischaemic brain injury—due to more risk factors and impaired cerebral autoregulation. Severe Hypoxic–ischaemic brain injury affects deep grey matter structures and the brain stem. Less severe injury tends to cause germinal matrix haemorrhage or periventricular leukomalacia (PVL).
US

•  Often normal in the first 2 days, look for areas of increased echogenicity.
•  The thalami are more commonly spared than in term Hypoxic–ischaemic brain injury.
•  Periventricular echogenicity suggests acute PVL; after 2 weeks, these areas become cystic (these resolve over time).

MRI

•  As with term Hypoxic–ischaemic brain injury, DWI most sensitive acutely at 3-5 days.
•  T2 hyperintensity develops at 1 week.
•  Ischaemic lesions adjacent to the ventricular trigone suggest PVL.