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"CHONDROSARCOMA"

“ Most common primary bone tumour in adults; more common in males, with a median age of onset of 45 years . Broad range of behaviour from ...

Most common primary bone tumour in adults; more common in males, with a median age of onset of 45 years. Broad range of behaviour from very slow growing to highly aggressive and metastasising. In total, 90% of cases are ‘conventional’ chondrosarcomas (other types include dedifferentiated chondrosarcoma, secondary chondrosarcoma, etc.). Hyperglycaemia paraneoplastic syndrome is common (up to 85%).
PLAIN FILM

•  Pelvis and femur (40%), spine and ribs (25%), shoulder and proximal humerus (15%).
•  Outside the hands and feet chondrosarcoma is five-times more common than enchondroma.
•  Central location most common, begins in the metaphysis and extends to diaphysis.
•  Well-defined lytic lesion, endosteal scalloping and thinning/destruction of the cortex.
•  Internal matrix is chondroid.
•  Large lesion (>5 cm).
•  Periositis (fluffy or lamellated).
•  Soft tissue mass.

MRI

•  Gold standard for pre-operative planning and post-operative surveillance.
•  Defines extent of the bone and soft tissue lesion.
•  Non-specific low signal on T1, high on T2 with enhancement post-contrast.