“ Also known as heterotopic ossification, this is a benign, self-limiting inflammatory process characterised by mixed bone (mature lamellar ...
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Also known as heterotopic ossification, this is a benign, self-limiting inflammatory process characterised by mixed bone (mature lamellar bone)/cartilaginous masses within skeletal muscle. There are three forms:
- traumatic (75%, any injury leading to severe rhabdomyolysis),
- neurogenic (brain injuries, cord trauma, etc.) and
- congenital (myositis ossificans progressiva).
New bone is surrounded by fibrotic connective tissue. Masses are painful.
• Soft tissue swelling initially.
• Floccular calcification begins to form after about 3 weeks.
• Lamellar bone begins to form after 6-8 weeks.
• Mature lesions may show a dense periphery (bone cortex) with a more lucent centre (medulla).
• Difficult to distinguish from malignancy (e.g. parosteal osteosarcoma, tends to have dense calcification centrally).
CT
• More sensitive than plain films
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