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NORMAL BONE MARROW CONVERSION

“ At birth, red (haematopoietic) marrow is present throughout the entire skeleton. Conversion of red to yellow (fatty) marrow occurs over a ...

At birth, red (haematopoietic) marrow is present throughout the entire skeleton. Conversion of red to yellow (fatty) marrow occurs over a period of about 20 years, beginning distally in the hands and feet and migrating proximally until red marrow remains only in the:

•  Axial skeleton
•  Skull
•  Vertebral column
•  Thoracic cage
•  Pelvic girdle
•  Humeral and femoral metaphyses.

Normal haematopoietic bone marrow may appear similar to malignant infiltration—location is a major discriminator.