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"XANTHOGRANULOMATOUS PYELONEPHRITIS (XGP)"

“ Chronic inflammatory change, usually from an obstructing (staghorn) calculus. Begins within the kidney. When advanced, it may involve the...

Chronic inflammatory change, usually from an obstructing (staghorn) calculus. Begins within the kidney. When advanced, it may involve the retroperitoneum. Treatment with antibiotics/nephrectomy.
US
•  Diffuse renal enlargement with central calculus
•  Hydronephrosis/pyonephrosis
•  Perinephric collection or soft tissue
CT
•  Rim-enhancing hypodense renal masses, central calculus, little or no excretion of contrast.
•  Look for aggressive perinephric and retroperitoneal extension.
Post-contrast CT scan of the abdomen showing a large, mixed-density lesion arising from the right kidney. Note a large staghorn calculus on the medial side of the mass. The findings are in keeping with xanthogranulomatous pyelonephritis.