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"EWING SARCOMA"

“ Second most common primary bone tumour of children and adolescents (after osteosarcoma). It accounts for 10% of primary bone tumours, and ...

Second most common primary bone tumour of children and adolescents (after osteosarcoma). It accounts for 10% of primary bone tumours, and 95% occur between 4 and 25 years of age (peak 10-15 years of age). Patients commonly present with a >6-month history of pain and swelling with or without fever.
PLAIN FILM 

•  75% are found in the pelvis and long bones (if the spine is involved, it is usually the sacrum, 6% overall).
•  Overall most common is the metadiaphyseal region of the femur.
•  Permeative or moth-eaten osteolysis.
•  Poor margination (wide zone of transition).
•  Cortical erosion.
•  Exuberant periostitis (lamellated or sunburst).
•  Soft tissue mass.

MRI

•  Marrow replacement, cortical destruction and soft tissue mass.
•  Lesion is intermediate on T1 and high signal on T2 and there is diffuse or peripheral enhancement with contrast.

NUCLEAR MEDICINE

•  Increased tracer uptake on scintigraphy, gallium scan and positron emission tomography (PET).
•  PET/CT is highly sensitive (88%) for staging and restaging.

Ewing sarcoma. Frontal radiograph of the tibia/fibula demonstrating a lesion within the metadiaphyseal region of the
fibula with a permeative appearance, wide zone of transition and periostitis.