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"ZOLLINGER-ELLISON SYNDROME"

In 90% of cases, this is secondary to gastrinoma , a gastrin-secreting islet cell tumour.  This leads to increased production of gastric HC...

In 90% of cases, this is secondary to gastrinoma, a gastrin-secreting islet cell tumour. 
This leads to increased production of gastric HCl. 
Patients present with pain, diarrhoea and recurrent ulcers. In total, 25% are associated with multiple endocrine neoplasia type-1.
BARIUM MEAL

•  Thickened gastric or duodenal folds.
•  Ulcers are most commonly found in the first part of the duodenum (10% have multiple ulcers).
•  Dilatation of proximal small bowel due to hypersecretion.