“ Means ‘smooth’, same as agyria (pachygyria = broad, flat gyri). Due to arrested neuronal migration . The brain looks as it should at 18-20...
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Means ‘smooth’, same as agyria (pachygyria = broad, flat gyri). Due to arrested neuronal migration. The brain looks as it should at 18-20 weeks of gestation. It is the most severe malformation of cortical development.
MRI
• Thickened, smooth cortex with slight indentation at the Sylvian fissures.
• May be localised to a single lobe and usually the cerebellum is spared.
• Dilated occipital horns of the lateral ventricles (i.e. colpocephaly).
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