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Ménétrier disease

This is a rare disease due to gastric gland hypertrophy, which sheds protein into the gut. In total, 10% of affected patients will get gastr...

This is a rare disease due to gastric gland hypertrophy, which sheds protein into the gut. In total, 10% of affected patients will get gastric cancer. Patients present with pain, weight loss, oedema, etc., due to protein loss.
BARIUM MEAL

•  Marked thickening and tortuosity of the rugae, though the stomach distends normally (unlike with malignancy).
•  The antrum is spared in 50%.
•  Folds alter in size and position during the examination.
•  Mucous hypersecretion causes dilution of contrast.
•  Small bowel fold thickening.
•  Ulceration due to achlorydia.

CT

•  Thickened gastric folds project into the gastric lumen.
•  The serosal contour is smooth.