“ Primarily idiopathic, but the pattern may also be associated with connective tissue disorders (e.g. s ystemic lupus erythematosus [SLE] a...
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Primarily idiopathic, but the pattern may also be associated with connective tissue disorders (e.g. systemic lupus erythematosus [SLE] and systemic sclerosis), other autoimmune diseases (rheumatoid arthritis) and may be drug induced (e.g. gold). Affects younger patients than IPF and responds well to steroid treatment.
Plain film
• Normal at first, then diffuse airspace opacities.
• Bilateral, symmetrical, sub-pleural ground-glass change with reticular opacities.
• Traction bronchiectasis and consolidation later in the disease.
• Ground-glass opacification dominates—not reticulation as with UIP.
• There may be honeycombing late in the disease (microcystic).
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