Autosomal dominant syndrome that causes multiple benign hamartomatous polyps ; more common in the stomach and small bowel . No malignant po...
Autosomal dominant syndrome that causes multiple benign hamartomatous polyps; more common in the stomach and small bowel. No malignant potential. (although the overlying mucosa may become dysplastic with an increased risk of an upper GI tract cancer)
It is the most common polyposis syndrome to involve the small intestine.
It can also appear in the large bowel, where polyps are larger, pedunculated and bleed.
There is a risk of malignant transformation in the bowel, as well as in the ovary, thyroid, testis, pancreas and breast.
• Intussusception is a common presentation
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